EU RESEARCHERS DEVELOP NEW MEANS TO ATTACK FUNGAL PATHOGENS
July 1st, 2007
BY KEITH NUTHALL SCIENTISTS from the European Molecular Biology Laboratory (EMBL) and the US have identified a new chemical compound that attacks hard-to-treat fungal infections. This 'AN2690' blocks the development of an enzyme that is crucial for the fungi to synthesise protein. "It has been very successful in clinical trials," said Dickon Alley, of project partner Anacor Pharmaceuticals. The blocked enzyme is called leucyl-tRNA synthetase, which is involved in translation, a final step of turning a gene's DNA code into a protein. This system has treated common ...
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